Twentyone Hotel

Via Cola Di Rienzo 23, Vaticano Prati, Rome, Italy - Halfway to Vatican
4.0 1904 reviews

The 4-star Twentyone Hotel Rome is situated in the Via Cola di Rienzo district, around a 25-minute walk from the aqueduct-fed rococo Trevi Fountain and features 88 rooms with views of the sea. The hotel provides a charging station for electric vehicles for EUR 35 per day on site.

Location

This Rome hotel is about 13 miles from Ciampino airport and 1 mile from such cultural venues as the Christian and art Vatican Museums. The Twentyone is about 10 minutes' drive from Stadio Olimpico Stadium and a short way from the large urban square "Piazza del Popolo". Guests might as well enjoy proximity to Piazza Cavour, situated 0.3 miles away. Colosseum Arena lies approximately 15 minutes' drive away, and Lepanto is within 5 minutes' walk of this property. The Twentyone Rome is 0.4 miles from Flaminio city rail and just moments from Maria Adelaide bus stop.

Rooms

The rooms at the Rome hotel have individual climate control and a central heating. Some of them comprise a balcony and a sitting area, appointed with a study desk. Providing a spa bathtub and a walk-in shower, some bathrooms come with dressing gowns and slippers.

Food & Drinks

Serving a wide assortment of dishes, Le Sicilianedde is within easy reach of the Twentyone.

Why choose Twentyone Hotel Rome

Select room
  • Spectacular views from rooms

  • Bistrò 21 offers gourmet dining

  • Connected to public transport

  • Beautiful modern interior design

Main amenities

  • Wi-Fi

  • 24-hour services

  • Express check-in/ -out

  • Fitness/Gym

  • On-site Dining

  • No Smoking

  • Child-friendly

  • Wheelchair access

  • Breakfast

  • Air conditioning

  • No pets allowed

General
  • Wi-Fi
  • 24-hour services
  • Express check-in/ -out
  • Fitness/Gym
  • On-site Dining
  • No Smoking
  • Child-friendly
  • Wheelchair access
  • Breakfast
  • Air conditioning
  • No pets allowed
1/30

Internet

  • Wi-Fi

Parking options

  • Parking

Shuttle

  • Paid airport shuttle

Activities

  • Fitness centre

Property services

  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Security
  • Luggage storage
  • Barber shop
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining options

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Packed lunches
  • Special diet menus

Business facilities

  • Fax/Photocopying

For kids

  • Cots
  • Children's buffet

Recreation

  • Garden area
  • Leisure/ TV room

For disabled guests

  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Toilet for disabled
  • Bathroom for disabled

In the rooms

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

In the bathroom

  • Free toiletries
  • Sink

Devices

  • Flat-screen TV
  • AM/FM alarm clock

Design

  • Carpeted floor

General facilities

  • Non-smoking rooms
  • Allergy-free rooms
  • Lift
  • Coffee shop
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Pets

  • No pets allowed

Important information

Check-in:
from 15:00 until 23:59
Check-out:
from 07:00 until 11:00
License number058091-ALB-00313,IT058091A1GZ5MCI9I
  • Children and extra beds
  • There are no cribs provided in a room.

Enter dates to see availability

From USD 82 per night
Check-in 7 May 2026
Check-out 8 May 2026
Guests 2 guests

Adults:

2

Children:

0
All rates verified
How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.
Special offers & deals Limited offer

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An exclusive discount – get up to 10% off when you book from your phone.

Summer Deal

Up to 15% off
Make the most of summer with up to 15% off and free breakfast – limited-time offer.

Members Only Rate

Up to 15% off
Join now to unlock up to 15% off on your dates – visible to members only.

Family Package Deal

Up to 20% off
Save up to 20% with special family packages that include your stay, meals, and fun for the kids..

Early Booking Discount

Up to 20% off
Save up to 20% when you book at least 30 days before your trip.

Rooms

Photos of Twentyone Hotel Rome

Location of Twentyone Hotel Rome

Via Cola Di Rienzo 23, Vaticano Prati, Rome, Italy

 -  Halfway to Vatican
Attractions
Great restaurants
Transportation

Places nearby

    Guest reviews of Twentyone Hotel Rome

    8.3 Very Good
    3670 reviews

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    100% Verified Reviews
    Enter dates to see availability
    From USD 82 per night
    Check-in 7 May 2026
    Check-out 8 May 2026
    Guests 2 guests

    Adults:

    2

    Children:

    0
    All rates verified
    How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.
    Check-in & out
    7 May 2026
    8 May 2026
    Guests
    2 guests
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    Twentyone Hotel
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    Details:

    Via Cola Di Rienzo 23, Rome, Italy

    Important information
    Twentyone Hotel
    Check-in:
    from 15:00 until 23:59
    Check-out:
    from 07:00 until 11:00
    License number058091-ALB-00313,IT058091A1GZ5MCI9I
    • Children and extra beds
    • There are no cribs provided in a room.